By F. Pietra
This, the newest contribution to the Tetrahedron natural Chemistry sequence, presents an built-in assessment of the range of average items with regards to biodiversity. the continued exploitation of organic assets, whereas retaining an efficient equilibrium on the earth, relies a lot at the conservation of biodiversity. To this finish, components one and concentrate on biodiversity from all viewpoints, whereas explaining the hyperlink with typical items. The 3rd part concentrates at the molecular-shape point, as a hyperlink to environment and biodiversity, whereas the fourth part tackles real functionalization, as a hyperlink to biodiversity at species point. half 5 addresses the diversification of those assets from biotechnology and chemical expertise, whereas the ultimate half is anxious with protecting ordinary product range on the earth.
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Extra info for Biodiversity and Natural Product Diversity
I ""::':"~ ............ ' ....... il) ! 11. Biological zonation of the oceans remains uncertain because of scarce ad hoc studies. However, the myriads of phenomena of association and parasitism typical of marine life suggest that areas of high macro-organismic biodiversity are also areas of high micro-organismic biodiversity. Anyway, microorganisms have a wider range o foccupancy than macroorganisms, comprising extreme conditions that the latter cannot endure. This receives specific attention in Chapter 10.
Patella from GBR: Wipf 2000A). , Bact. from PNG: Gerard 1999); phakellistatins: 8 (Phakelliaspp. Axinel. and Stylotella aurantium Kelly-Borges and Bergquist, Halichon. Porif. from W Pacific: Delbert 1997). 48) IoloatJn B a c t . N~==O N 0 0 0%. 55) ' A$cid. ulithiacydamide A s c i d . 55) "statin 8 Porif Chapter 7. 32) Aplysamines and hemibastadins: (Verongida, Porif. from Hawaii and PNG: Pettit, 1996); bastadins: (lanthella spp. , Verongida, Porif. from W Pacific: Franklin 1996); caprolactins: (unident.
This is but a particular ease of the general tenet that the wider the distribution, the narrower the diversity of natural products. The matter is complex, however, because the same molecule may arise from different biosynthetic pathways, implying different genes. To this category belong metabolites that play different functions in phylogenetically distant organisms, like the prostaglandins (Pietra 1995), although a firm conclusion about the biosynthetic pathways is still 62 Part 111. Natural product diversity at ecosystem level far to come (Varvas 1994; Hess 1999).