Download Bioaccumulation and Occurrence of Endocrine- Disrupting by Geyer H. J., Rimkus G. G., Scheunert I. PDF

By Geyer H. J., Rimkus G. G., Scheunert I.

Show description

Read Online or Download Bioaccumulation and Occurrence of Endocrine- Disrupting Chemicals (EDCs), Pers[...]umans(en)(166s) PDF

Similar chemistry books

Catalysis in application: [proceedings of the International Symposium on Applied Catalysis to be held at the University of Glasgow on 16-18 July 2003]

Catalysis in program provides a photo of the main up to date advancements within the box of utilized catalysis. assurance is especially within the components of hydrogenation, dehydrogenation, chiral catalysis, environmental catalysis and catalyst deactivation, combining a special mixture of chemistry and chemical engineering.

Boron Chemistry–4. Plenary and Session Lectures Presented at the Fourth International Meeting on Boron Chemistry, Salt Lake City and Snowbird, Utah, USA, 9–13 July 1979

Boron Chemistry - four covers the court cases of the Fourth foreign assembly on Boron Chemistry. The booklet includes invited plenary lectures and consultation lectures given through the convention. The textual content discusses a number of issues pertaining to boron chemistry, resembling conceptual advances in boron chemistry; cluster compounds and carboranes; and organometallic compounds containing boron ligands, boron clusters, or carboranes.

Additional resources for Bioaccumulation and Occurrence of Endocrine- Disrupting Chemicals (EDCs), Pers[...]umans(en)(166s)

Sample text

Chemical structure Molecular formula and molecular mass [g mol –1] RPP a (%) Water Solubility (mg l–1) log KOW Detected in water, sludge, sediment, algae, mussel, or fish. 8 l river water, activated sludge, effluents from STPsW 2. J. Geyer et al. 07 was found in effluents in USA, when it was used as a growth – promoting agent in large amounts. 87 Chloro-tris (4-methoxy-phenyl)ethylene Bioaccumulation and Occurrence of Endocrine-Disrupting Chemicals (EDCs) 3. Synthetic non-steroidal estrogens 4.

The phenomenon was termed “imposex” or “pseudohermaphrodism” [65]. Recent studies by Oehlmann et al. [114] indicated that TBT increased the testosterone titers in female gastropods. Simultaneous exposure to TBT and to the antiandrogen cyproterone acetate suppressed imposex development completely in Nucella lapillus and greatly reduced imposex in Hinia reticulata. These results proved that the imposex inducing-effects of TBT are mediated by an increasing androgen level and are not caused directly by TBT itself.

Competitive estrogen antagonists are the most specific antiestrogens. Such compounds are used in the treatment of infertility, breast cancer and osteoporosis. Examples are trans-clomiphene and its metabolite trans–4-hydroxyclomiphene, tamoxifen and raloxifene. Clomiphene is used as a fertility agent. This drug can bind to the estrogen receptor, thereby blocking activation by endogenous estrogens. The breast cancer adjuvant non-steroidal pharmaceutical agent tamoxifen and its metabolite, 4-hydroxy tamoxifen, exhibit both antiestrogenic and estrogenic activities [149, 294].

Download PDF sample

Rated 4.36 of 5 – based on 20 votes